Coming Soon! Profile JAK/Stat, PI3K/AKT, and MAPK/ERK inhibition with ClariPATHWAY™ assays

Reversible phosphorylation leads to the transmission of cellular signals through a complex and intertwined system of pathways.  At CAI, we are introducing ClariPATHWAY™ assays to assess inhibitor activity against specific cell pathways in the context of endogenous protein expression. IC50 and potency information obtained from these cell-based assays is valuable for determining mechanism of action, activity, selectivity, and the potential for off-target effects against the given signal transduction pathways.

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Coming Soon, ClariPATHWAY™ inhibition assays for the following:

JAK/STAT

PI3K/AKT

MAPK/ERK